The Incretin Effect of Yerba Maté (Ilex paraguariensis) Is Partially Dependent on Gut-Mediated Metabolism of Ferulic Acid
Peer-ReviewedJournal
2025-02-09
Unicity Research
This peer-reviewed study found that Unimate increased GLP-1 gene expression and raised circulating active GLP-1 by approximately 45% compared with control. Researchers also identified a gut-mediated pathway in which microbes convert ferulic acid into dihydroferulic acid, a compound that strongly stimulated GLP-1 production in intestinal cells. The findings help explain how Unimate supports the body’s natural GLP-1 response.
GLP-1Gut HealthMetabolic HealthUnicity ProductUnimate
Attribution & License
Elijah T. Cooper-Leavitt, Marley J. Shin, Colson G. Beus, Alden T. Chiu, Genevieve Parker, Jack H. Radford, Ethan P. Evans, Isaac T. Edwards, Juan A. Arroyo, Paul R. Reynolds, and Benjamin T. Bikman. “The Incretin Effect of Yerba Maté (Ilex paraguariensis) Is Partially Dependent on Gut-Mediated Metabolism of Ferulic Acid.” Nutrients. 2025;17(4):625. doi:10.3390/nu17040625.
Copyright: The authors
License: CC BY 4.0